🌿 SKIN1004 Lab in Nature Madagascar Centella Azelaic Acid 10 Ampoule 30ml

Blemish Care • Visible Redness • Post-Blemish Marks • Sebum Balance • Texture

Meet SKIN1004 Lab in Nature Madagascar Centella Azelaic Acid 10 Ampoule, a targeted Korean ampoule designed for blemish-prone skin, visible redness, uneven texture and post-blemish marks.

What makes this formula especially interesting is SKIN1004's 3X Azelaic Active Formula (11.5%), combining 10% Azelaic Acid + 1% Potassium Azeloyl Diglycinate + 0.5% Azelamide MEA. It's paired with Panthenol, Madagascar Centella Asiatica, Sodium Hyaluronate, Beta-Glucan and Licorice Root Extract for supportive soothing and hydration.

⚡ Quick Answer: What Is SKIN1004 Azelaic Acid 10 Ampoule?

SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule is a 30ml Korean treatment ampoule featuring 10% Azelaic Acid as part of an 11.5% triple azelaic-active complex. It is designed for blemish-prone skin to help improve visible redness, post-blemish marks, excess sebum, clogged-looking pores and uneven skin texture while providing lightweight hydration.

💚 Why You'll Love It

♡ 10% Azelaic Acid

♡ 11.5% total 3X Azelaic Active Formula

♡ Targets blemish-prone skin

♡ Helps soothe visible redness

♡ Helps improve post-blemish marks

♡ Supports more even-looking skin tone

♡ Helps balance excess sebum

♡ Supports smoother-looking skin texture

♡ Madagascar Centella Asiatica

♡ Panthenol + Beta-Glucan

♡ Sodium Hyaluronate

♡ Licorice Root Extract

♡ Lightweight, watery texture

♡ Non-comedogenic tested

♡ Sensitive-skin irritation tested

♡ Low-pH, low-irritation formula

🧪 What Is the 3X Azelaic Active Formula?

This is the feature that really differentiates the SKIN1004 ampoule from many standard 10% Azelaic Acid products.

SKIN1004's 3X Azelaic Active Formula totals 11.5%:

🌿 Azelaic Acid — 10%

The primary active, targeting the appearance of blemishes, visible redness, uneven tone and texture.

💧 Potassium Azeloyl Diglycinate — 1%

An azelaic-acid derivative included to complement the formula's sebum-balancing and skin-conditioning approach.

✨ Azelamide MEA — 0.5%

A second azelaic-derived ingredient completing the triple-active system.

SKIN1004 also states that the formula uses encapsulated Azelaic Acid to improve stability and support effective delivery.

🌱 Madagascar Centella + Soothing Care

This product belongs to SKIN1004's Lab in Nature line, which combines nature-derived ingredients such as Madagascar Centella Asiatica with targeted active ingredients.

Alongside the azelaic complex, you'll find:

Centella Asiatica Extract — soothing skin care

Panthenol — hydration and barrier support

Beta-Glucan — moisturizing and skin-conditioning support

Sodium Hyaluronate — lightweight hydration

Allantoin — soothing skin conditioning

Licorice Root Extract — complements the formula's tone-care focus

That balance is important because this isn't simply a high-active treatment—the formula also includes ingredients designed to keep skin feeling hydrated and comfortable.

🧴 Texture & Finish

SKIN1004 describes the texture as lightweight and watery.

It spreads easily, absorbs quickly and leaves a fresh, non-sticky finish, making it suitable for both morning and evening routines.

🎯 Who Is It Best For?

🌿 Blemish-Prone Skin
This is the product's primary target. SKIN1004 has also completed non-comedogenic testing on the formula.

🌹 Visible Redness
The ampoule is specifically formulated to help soothe the appearance of redness.

✨ Post-Blemish Marks
A good option when breakouts leave visible marks or uneven-looking tone.

💧 Oily Skin
The formula targets excess sebum without relying on a heavy moisturizer-like texture.

🫧 Congested-Looking Pores
SKIN1004 reports testing related to pore-clogging concerns and sebum levels.

🤍 Sensitive Skin
SKIN1004 describes it as a low-pH, low-irritation formula and reports sensitive-skin irritation testing. Because it still contains 10% Azelaic Acid, gradual introduction is the better approach.

📊 SKIN1004 Clinical Testing

SKIN1004 reports several human application test results for the current formula.

After four weeks, the brand reports:

37.12% improvement in skin turnover

53.98% reduction in sebum levels

12.25% improvement in a pore-clogging-related skin index

The brand also reports:

199.91% improvement in immediate temporary hydration after one use

24.95% improvement in soothing externally irritated skin after one use

Testing was also completed for skin-tone improvement, dark-spot area reduction, non-comedogenicity, sensitive-skin irritation and primary skin irritation. These are manufacturer-reported test results; individual results can vary.

💕 How to Use

This is one product where starting slowly is important.

First Week

Apply a pea-sized amount to areas of concern every other day.

After Your Skin Adjusts

Gradually increase the amount and frequency according to your skin's tolerance.

SKIN1004's recommended regular amount is approximately 2–3 drops applied evenly to the skin.

For specific areas of concern, an additional thin layer can be applied.

Follow with a soothing moisturizer.

☀️ Morning

Cleanser → Toner → SKIN1004 Azelaic Acid 10 Ampoule → Moisturizer → Sunscreen

🌙 Evening

Cleanser → Toner → SKIN1004 Azelaic Acid 10 Ampoule → Moisturizer

SKIN1004 specifically instructs users to finish the morning routine with sunscreen.

🇨🇦 Edmonton Dry-Skin Tip

If you live in Edmonton or elsewhere in Alberta, don't focus only on the active ingredient.

Our dry climate and indoor heating can make a routine built entirely around blemish-control products feel unnecessarily drying.

A better approach is:

Azelaic Acid Treatment → Barrier Moisturizer

For example:

SKIN1004 Azelaic Acid 10 Ampoule → PURITO Mighty Bamboo Panthenol Cream

If you're oily but still dehydrated, use a smaller amount of moisturizer rather than automatically skipping it.

🆚 SKIN1004 Azelaic Acid 10 vs ANUA Azelaic Acid 10

💚 Choose SKIN1004 if...

Your priorities are:

Blemishes + excess sebum + clogged-looking pores + texture + post-blemish marks

and you want a more specialized triple azelaic-active system.

💗 Choose ANUA if...

Your priorities are:

Redness + blemish-prone skin + hydration/barrier support

and you like a formula containing Ceramide NP, Squalane and Zinc PCA alongside 10% Azelaic Acid.

Neither is automatically better for everyone—the surrounding formula and your skin's tolerance matter.

❓ Frequently Asked Questions

How much Azelaic Acid is in SKIN1004 Azelaic Acid 10 Ampoule?

It contains 10% Azelaic Acid.

However, SKIN1004's complete 3X Azelaic Active Formula is 11.5%, consisting of 10% Azelaic Acid, 1% Potassium Azeloyl Diglycinate and 0.5% Azelamide MEA.

Is SKIN1004 Azelaic Acid 10 good for acne-prone skin?

SKIN1004 specifically designed it for blemish-prone skin and reports that the formula has completed non-comedogenic testing.

For cosmetic product copy, it's more accurate to say it supports blemish-prone skin rather than promising to treat acne.

Does it help with redness?

Yes. Visible redness soothing is one of SKIN1004's stated benefits for this product.

Does it help with dark spots after acne?

The formula is designed to improve the appearance of post-blemish marks and uneven-looking tone, and SKIN1004 reports testing for dark-spot area reduction and skin-tone improvement.

Is it good for oily skin?

It is particularly interesting for oily and blemish-prone skin because SKIN1004 specifically targets sebum balancing, reporting a 53.98% reduction in sebum levels after four weeks in its human application testing.

Can sensitive skin use it?

SKIN1004 describes it as a low-pH, low-irritation formula and reports sensitive-skin irritation testing. However, it's still a 10% Azelaic Acid treatment, so beginners should follow the brand's adjustment period and start every other day.

Can I use it every day?

Potentially, after your skin adjusts.

SKIN1004 specifically recommends using it every other day during the first week and then gradually increasing frequency.

Can I use SKIN1004 Azelaic Acid with Niacinamide?

These ingredients can generally be part of the same skincare routine. If you're using a concentrated Niacinamide treatment such as a 10% formula, introduce combinations gradually rather than adding several actives at once.

Can I use it with Retinol or Retinal?

If you're new to either ingredient, alternating nights is a simple approach:

Night 1: Azelaic Acid → Moisturizer
Night 2: Retinol/Retinal → Barrier Moisturizer

Once your skin is comfortable, your routine can be adjusted according to tolerance.

Can I use it with AHA or BHA?

Multiple active treatments can increase the chance of irritation. If you're already using AHA/BHA exfoliation, consider using them on different nights while your skin adjusts to Azelaic Acid.

📝 Full Ingredients

Water, Azelaic Acid, Hydroxypropyl Cyclodextrin, Disodium Phosphate, Pentylene Glycol, Propanediol, Potassium Azeloyl Diglycinate, Maltodextrin, Azelamide MEA, Panthenol, Butylene Glycol, 1,2-Hexanediol, Glycerin, Ethylhexylglycerin, Allantoin, Centella Asiatica Extract, Melia Azadirachta Leaf Extract, Biosaccharide Gum-1, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Beta-Glucan, Centella Asiatica Leaf Extract, Phellinus Linteus Extract, Tocopherol, Citric Acid, Sodium Citrate, Glycyrrhiza Glabra (Licorice) Root Extract.

Ingredient lists can change. Please refer to the product packaging received for the most current ingredient information.

📦 Product Details

Brand: SKIN1004
Collection: Lab in Nature
Product: Madagascar Centella Azelaic Acid 10 Ampoule
Size: 30 mL
Product Type: Blemish / Redness Care Ampoule
Azelaic Acid: 10%
3X Azelaic Active Formula: 11.5%
Best For: Blemish-Prone • Oily • Redness-Prone • Uneven Texture
Texture: Lightweight Watery Ampoule
Finish: Fresh, Non-Sticky
Non-Comedogenic Tested: Yes
Sensitive-Skin Irritation Tested: Yes